Treatment for vitamin B1, B6, and B12 deficiency syndrome includes vitamin B1, B6, and B12. Additionally, it is indicated for the supportive management of neuritis & non-inflammatory diseases of the nerves, such as
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Vitamin B1 helps to maintain healthy neurons, lifts the spirits, and fortifies the heart in addition to converting carbs, fatty acids, and amino acids into energy. Vitamin B6 aids in the production of red blood cells (RBCs), proteins, and neurotransmitters like serotonin, the release of stored energy, the prevention of CVS illnesses and stroke, the reduction of depression, and the relief of insomnia. Vitamin B12 lowers the risk of heart illnesses, protects against anemia, helps to avoid depression, is crucial for RBC formation, and is needed for cell replication. It also lessens nerve discomfort, numbness, and tingling. Vitamin components are effectively absorbed when taken orally. Breast milk contains it, and it is broadly disseminated to most tissues. Thiamine is mostly present in the cell as diphosphate. Thiamine is not much retained in the body, and excess levels are either eliminated in the urine as unaltered thiamine or as metabolites. Following oral administration of pyridoxine, pyridoxal, and pyridoxamine, the GIT rapidly absorbs them and converts them to the active forms of pyridoxal phosphate and pyridoxamine phosphate. They are mostly stored in the liver, where they are oxidized to 4-pyridoxal acid and other inactive metabolites that are eliminated by urination. Greater amounts of the dosage are excreted unaltered in the urine proportionately when the dose is increased.
Use in children:
No overdosage symptoms are to be expected in the recommended dosage. If there is a known overdose then treatment is symptomatic & supportive.
No interaction is found
Vitamin B1, Vitamin B6, and Vitamin B12 are contraindicated in patients on levodopa therapy, and in patients with hypersensitivity to any of the ingredients of the preparation.
Generally well tolerated but allergic reactions may be observed in a few cases.
Oral tablet form is recommended but due to the presence of benzyl alcohol, injection is not recommended during pregnancy & lactation.
Cyanocobalamin should not be given in patients with subacute degeneration of the spinal cord. Cyanocobalamin is not a suitable to form of vitamin B12 for the treatment of optic neuropathies associated with raised plasma concentrations of cyanocobalamin.
Keep out of reach of children. Store in a cool (below 25°C temperature) and dry place, protected from light.
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